Neurophysiology

Publications Jack A Benson

1. BENSON, J.A. (1970) Locomotor activity cycles in the lizard Hoplodactylus pacificus. Undergraduate research dissertation, Auckland University. 

2. BENSON, J.A. (1973) An analysis of the activity rhythm of Talorchestia quoyana. Master's Thesis, Auckland University.

3. BENSON, J.A. and LEWIS, R.D. (1976) An analysis of the activity rhythm of the sand beach amphipod, Talorchestia quoyana. J. Comp. Physiol. 105, 339-352. 

4. BENSON, J.A. (1976) The circadian rhythm of activity in the lizard Hoplodactylus pacificus, and its possible taxonomic use. Tane 22, 119-128. 

5. BENSON, J.A. (1976) Further investigations of the generation and control of the circadian rhythm of compound action potentials from the eye of Aplysia. Doctoral Thesis, State University of New York at Albany. 

6. BENSON, J.A. (1977) Entrainment of a circadian rhythm of activity in an amphipod by skeleton photoperiods. J. interdiscipl. Cycle Res. 8, 37-45. 

7. BENSON, J.A. and JACKLET, J.W. (1977) Circadian rhythm of output from neurones in the eye of Aplysia. I. Effects of deuterium oxide and temperature. J. exp. Biol. 70, 151-166. 

8. BENSON, J.A. and JACKLET, J.W. (1977) Circadian rhythm of output from neurones in the eye of Aplysia. II. Effects of cold pulses on a population of coupled oscillators. J. exp. Biol. 70, 167-181. 

9. BENSON, J.A. and JACKLET, J.W. (1977) Circadian rhythm of output from neurones in the eye of Aplysia. III. Effects of light on clock and receptor output measured in the optic nerve. J. exp. Biol. 70, 183-194. 

10. BENSON, J.A. and JACKLET, J.W. (1977) Circadian rhythm of output from neurones in the eye of Aplysia. IV. A model of the clock: differential sensitivity to light and low temperature. J. exp. Biol. 70, 195-211. 

11. TREHERNE, J.E., BENSON, J.A. and SKAER, H. le B. (1977) Axonal accessibility and adaptation to osmotic stress in an extreme osmoconformer. Nature (Lond.) 269, 430-431.

12. SKAER, H. le B., TREHERNE, J.E., BENSON, J.A. and MORETON, R.B. (1978) Axonal adaptations to osmotic and ionic stress in an invertebrate osmoconformer (Mercierella enigmatica Fauvel). I. Ultrastructure and electrophysiological observations on axonal accessibility. J. exp. Biol. 76, 191-204.

 13. BENSON, J.A. and TREHERNE, J.E. (1978) Axonal adaptations to osmotic and ionic stress in an invertebrate osmoconformer (Mercierella enigmatica Fauvel). II. Effects of ionic dilution on the resting and action potentials. J. exp. Biol. 76, 205-219.

14. BENSON, J.A. and TREHERNE, J.E. (1978) Axonal adaptations to osmotic and ionic stress in an invertebrate osmoconformer (Mercierella enigmatica Fauvel). III. Adaptations to hyposmotic dilution. J. exp. Biol. 76, 221-235.

15. BENSON, J.A. (1980) Burst reset and frequency control of the neuronal oscillators in the cardiac ganglion of the crab, Portunus sanguinolentus. J. exp. Biol. 87, 285-313.

16. DRUMMOND, A.H., BENSON, J.A. and LEVITAN, I.B. (1980) Serotonin-induced hyperpolarization of an identified Aplysia neuron is mediated by cyclic AMP. Proc. Natl. Acad. Sci. USA 77, 5013-5017.

 17. BENSON, J.A. (1980) A cAMP analogue inhibits compound action potential production and phase shifts the circadian clock in the isolated eye of Aplysia. Comp. Biochem. Physiol. 67C, 195-198.

18. LEVITAN. I.B. and BENSON, J.A. (1981) Neuronal oscillators in Aplysia: modulation by serotonin and cyclic AMP. Trends NeuroSci. 4, 38-41.

19. BENSON, J.A., SULLIVAN, R.E., WATSON. W.H. and AUGUSTINE, G.J. (1981) The neuropeptide proctolin acts directly on Limulus cardiac muscle to increase the amplitude of contraction. Brain Res. 213, 449-454.

20. BENSON, J.A. (1981) Synaptic and regenerative responses of cardiac muscle fibres in the crab, Portunus sanguinolentus. J. comp. Physiol. 143, 349-356.

21. WATSON, W.H., AUGUSTINE, G.J., BENSON, J.A. and SULLIVAN, R.E. (1983) Proctolin and an endogenous proctolin-like peptide enhance the contractility of the Limulus heart. J. exp. Biol. 103, 55-73.

 22. BENSON, J.A. and LEVITAN, I.B. (1983) Serotonin increases an anomalously rectifying K+ current in the Aplysia neuron R15. Proc. Natl. Acad. Sci. USA 80, 3522-3525.

23. BENSON, J.A., ADAMS, W.B., LEMOS, J.R., NOVAK-HOFER, I. and LEVITAN, I.B. (1983) Molecular mechanisms of neuromodulator action on a target neurone. In: Molluscan Neuro-Endocrinology (eds. J. Lever and H.H. Boer) North-Holland Publishing Company, Amsterdam and New York. pp. 31-37. 

24. MILLER, M.W., BENSON, J.A. and BERLIND, A. (1984) Excitatory effects of dopamine on the cardiac ganglia of the crabs Portunus sanguinolentus and  Podophthalmus vigil. J. exp. Biol. 108, 97-118.

25. BENSON, J.A. (1984) Octopamine alters rhythmic activity in the isolated cardiac ganglion of the crab, Portunus sanguinolentus. Neurosci. Letters 44, 59-64.

26. BENSON, J.A. and COOKE, I.M. (1984) Driver potentials and the organization of rhythmic bursting in crustacean ganglia. Trends NeuroSci. 7, 85-91.

27. ADAMS, W.B. and BENSON, J.A. (1985) The generation and modulation of endogenous rhythmicity in the Aplysia bursting pacemaker neurone R15. Prog. Biophys. molec. Biol. 46, 1-49.

28. LEMOS, J.R., ADAMS, W.B., NOVAK-HOFER, I., BENSON, J.A. and LEVITAN, I.B. (1986) Regulation of neuronal activity by protein phosphorylation. In: Neural Mechanisms of Conditioning. (eds. D.L. Alkon and C.D. Woody) Plenum Press, New York and London. pp. 397-420.

29. BENSON, J.A. and ADAMS, W.B. (1987) The control of rhythmic neuronal firing. In: Neuromodulation. The biochemical control of neuronal excitability. (eds. L.K. Kaczmarek and I.B. Levitan) Oxford University Press, New York. pp. 100- 118.

 30. LEES, G., BEADLE, D.J., NEUMANN, R. and BENSON, J.A. (1987) Responses to GABA by isolated insect neuronal somata: pharmacology and modulation by a benzodiazepine and a barbiturate. Brain Res. 401, 267-278.

31. ADAMS, W.B. and BENSON, J.A. (1987) Ion channel distribution and the generation and modulation of endogenous bursting activity in molluscan and crustacean neurones. In: Neurobiology, Molluscan Models. (eds. H.H. Boer, W.P.M. Geraerts and J. Joose) Mon. Kon. Ned. Akad. Wetensch., North  Holland Publ. Co., Amsterdam and New York. pp. 178-185.

32. NEUMANN, R., LEES, G., BEADLE, D.J. and BENSON, J.A. (1987) Responses to GABA and other neurotransmitters in insect central neuronal somata in vitro. In: Sites of Action for Neurotoxic Pesticides. (eds. R.M. Hollingworth and M.B. Green), American Chemical Society, Washington, D.C., pp. 25- 43.

33. BENSON, J.A. (1988) Bicuculline blocks the response to acetylcholine and nicotine but not to muscarine or GABA in isolated insect neuronal somata. Brain Res. 458, 65-71.

34. BENSON, J.A. (1988) Transmitter receptors on insect neuronal somata: GABAergic and cholinergic pharmacology. In: Neurotox '88: The Molecular Basis of Drug and Pesticide Action. (ed. G.G. Lunt) Elsevier Science Publishers, Amsterdam. pp. 193-206.

35. BENSON, J.A. (1988) Pharmacology of a locust thoracic ganglion somal nicotinic acetylcholine receptor. In: Nicotinic Acetylcholine Receptors in the Nervous System. NATO ASI Series H Vol. 25 (eds. F. Clementi, C. Gotti, E. Sher) Springer Verlag, Berlin, Heidelberg. pp. 127-140.

36. BENSON, J.A. and ADAMS, W.B. (1989) The ionic mechanisms of endogenous activity in molluscan burster neurons. In: Neuronal and Cellular Oscillators. (ed. J.W. Jacklet) Marcel Decker, New York and Basel. pp. 87-120.

37. ADAMS, W.B. and BENSON, J.A. (1989) Rhythmic neuronal burst generation: experiment and theory. In: Cell to Cell Signalling: From Experiments to Theoretical Models. (ed. A. Goldbeter) Academic Press, London. pp. 29-45.

38. BENSON, J.A. (1989) A novel GABA receptor in the heart of a primitive arthropod, Limulus polyphemus. J. exp. Biol. 147, 421-438.

39. BENSON, J.A. (1989) Insect nicotinic acetylcholine receptors as targets for insecticides. In: Progress and Prospects in Insect Control. (ed. N.R. McFarlane) BCPC Monograph No.43, British Crop Protection Council, Farnham,  England. pp. 59-70.

40. RUDER, F., GUYER, W., BENSON, J.A. and KAYSER, H. (1991) The thiourea insecticide/acaricide diafenthiuron has a novel mode of action - inhibition of mitochondrial respiration by its carbodiimide product. Pestic. Biochem. Physiol. 41, 207-219.

41. BERMUDEZ, I., BEADLE, D.J. and BENSON, J.A. (1991) Multiple serotonin-activated currents in isolated, neuronal somata from locust thoracic ganglia. J. exp. Biol. 165, 43-60.

42. BENSON, J.A. (1992) Natural and synthetic toxins at insect receptors and ion channels: the search for insecticide leads and target sites. In: Neurotox '91: Molecular Basis of Drug and Pesticide Action. (ed. I.R. Duce) Elsevier Applied Science, London. pp. 57-70.

 43. BENSON, J.A., SCHUERMANN, F., KAUFMANN, L., GSELL, L. and PIEK, T. (1992) Inhibition of dipteran larval neuromuscular synaptic transmission by analogues of philanthotoxin-433: a structure-activity study. Comp. Biochem. Physiol. C 102, 267-272.

44. BENSON, J.A. (1992) Electrophysiological pharmacology of the nicotinic and muscarinic acetylcholine responses of isolated neuronal somata from locust thoracic ganglia. J. exp. Biol. 170, 203-233.

45. BENSON, J.A. (1993) The electrophysiological pharmacology of neurotransmitter receptors on locust neuronal somata. In: Comparative Molecular Neurobiology. (ed. Y. Pichon) Birkhäuser Verlag, Basel. pp. 389-412

 46. BENSON, J.A., KAUFMANN, L., HUE, B., PELHATE, M., SCHUERMANN, F., GSELL, L. and PIEK, T. (1993) The physiological action of analogues of philanthotoxin-433 at insect nicotinic receptors. Comp. Biochem. Physiol. C 105, 303-310

47. BACKUS, K.H., ARIGONI, M., DRESCHER, U., SCHEURER, L., MÖHLER, H. and BENSON, J.A. (1993) Stoichiometry  of a recombinant GABAA receptor deduced from mutation induced rectification. NeuroReport 5, 285-288.

48. BENSON, J.A. (1994) Why natural products? In: New strategies for locust control in natural product and receptor research (eds. H. Rembold, J.A. Benson, H. Franzen, B. Weickel & F.A. Schulz) ATSAF, Bonn. pp. 66-71. 

 49. GÜNTHER, U., BENSON, J., BENKE, D., FRITSCHY, J.-M., REYES, G., KNOFLACH, F., CRESTANI, F., AGUZZI, A., ARIGONI, M., LANG, Y., BLUETHMANN, H., MOHLER, H. and LÜSCHER, B. (1995) Benzodiazepine-insensitive mice generated by targeted disruption of the γ2 subunit gene of GABAA receptors. Proc. natl. Acad. Sci. USA 92, 7749-7753.

50. MÖHLER, H., BENKE, D., BENSON, J., LÜSCHER, B. and FRITSCHY, J.M. (1995) GABAA-receptor subtypes in vivo: cellular localization, pharmacology and regulation. In: GABAA Receptors and Anxiety: From Neurobiology to Treatment. (eds. G. Biggio, E. Sanna & E. Costa) Raven Press, New York pp. 41-56.

51. MÖHLER, H., FRITSCHY, J.M., LÜSCHER, B., RUDOLPH, U., BENSON, J. and BENKE, D. (1996) The GABAA receptors. From subunits to diverse functions. In: Ion Channels. Vol. 4. (ed. T. Narahashi) Plenum Press: New York pp. 89-113.

52. KNOFLACH, F., BENKE, D., WANG, Y., L. SCHEURER, H. LÜDDENS, HAMILTON, B., CARTER, D.B., MÖHLER, H. and BENSON, J.A. (1996) Pharmacological modulation of the diazepam-insensitive recombinant GABAA receptors α4βγ2 and α6βγ2. Molec. Pharmacol. 50, 1253-1261.

53. MÖHLER, H., BENKE, D., BENSON, J., LÜSCHER, B., RUDOLPH, U. and FRITSCHY, J.M. (1996) Diversity in structure, pharmacology, and regulation of GABAA-receptors. In: The GABA Receptors (eds. S.F. Enna & N.G. Bowery) Humana Press Inc., Totawa, NJ. pp. 11-36. 

54. MÖHLER, H., FRITSCHY, J.M., BENKE, D., BENSON, J., RUDOLPH, U. and LÜSCHER, B. (1996) GABAA-receptor subtypes: pharmacological significance and mutational analysis in vivo. In: GABA: Receptors, Transporters and Metabolism (eds. C. Tanaka and N. Bowery) Birkhäuser Verlag, Basel. pp. 157-171. 

55. BENSON, J.A. (1997) Sodium channel targeted toxins. In: Guidebook to Protein Toxins and their Use in Cell Biology. (eds. R. Rappuoli & C. Montecucco) Oxford University Press, Oxford. pp. 115-118. 

56. BENSON, J.A., LÖW, K., KEIST, R., MOHLER, H. and RUDOLPH ,U.  (1998) Pharmacology of recombinant γ-aminobutyric acidA receptors rendered diazepam-insensitive by point-mutated α-subunits. FEBS Letters 431, 400-404.  

57. MOHLER, H., LUSCHER, B., FRITSCHY, J.-M.,BENKE, D., BENSON, J., RUDOLPH, U. (1998) GABAA-receptor assembly in vivo: lessons from subunit mutant mice. Life Sci. 62, 1611-1615. 

58. ESSRICH, C., LOREZ, M., BENSON, J.A., FRITSCHY, J.-M. and LÜSCHER, B. (1998) Postsynaptic clustering of major GABAA receptor subtypes requires the γ2 subunit and gephyrin. Nature Neuroscience 1, 563-571. 

59. RUDOLPH, U., CRESTANI, F., BENKE, D., BRÜNIG, I., BENSON, J.A., FRITSCHY,  J.-M., MARTIN, J.R., BLUETHMANN, H. and MÖHLER, H. (1999) Benzodiazepine actions mediated by specific γ-aminobutyric acidA receptor subtypes. Nature 401, 796-800.  

60. BAER, K., ESSRICH, C., BENSON, J.A., BENKE, D., BLÜTHMANN, H., FRITSCHY,  J.-M. and LÜSCHER, B. (1999) Postsynaptic clustering of γ-aminobutyric acid type A receptors by the γ3 subunit in vivo. Proc. Natl. Acad. Sci. USA 96, 12860-12865. 

61. LOREZ, M., BENKE, D., LÜSCHER, B., MOHLER, H. and BENSON, J.A. (2000) Single-channel properties of neuronal GABAA receptors from mice lacking the γ2 subunit. J. Physiol. (Lond.) 527,11-31. 

62. LÖW, K., CRESTANI, F., KEIST, R., BENKE, D., BRÜNIG, I., BENSON, J.A., FRITSCHY,  J.-M., RÜLICKE, T., BLUETHMANN, H. MÖHLER, H. and RUDOLPH, U. (2000) Molecular and neuronal substrate for the selective attenuation of anxiety. Science 290,131-134. 

63. FORSTER, I.C., HARVEY, R.J., DARLISON, M.G. and BENSON, J.A. (2001) Expression and functional pharmacology of the GABAA receptors containing the chicken brain γ4 subunit. Eur.J.Pharmacol. 419, 1-7.

64. BRÜNIG, I., PENSCHUCK, S., BERNINGER, B., BENSON, J., and FRITSCHY, J.-M. (2001) BDNF reduces miniature inhibitory postsynaptic currents by rapid downregulation of GABAA receptor surface expression. Eur. J. Neurosci., 13, 1320-1328

Back to Neurphysiology